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Intensive BP Lowering Harmful in Acute Ischemic StrokeThe ENCHANTED2/MT trial, which was investigating intensive lowering of blood pressure in acute ischemic stroke patients after
mechanical thrombectomy, has been stopped early due to safety concerns.
Medscape Medical News, Oct 28, 2022
Combo Thrombolytic Approach Fails to Reduce ICH in StrokeThe DUMAS study showed no benefit on the primary outcome of all ICH with low-dose alteplase followed by mutant pro-urokinase;
but there were promising signs of a potential reduced bleeding risk.
Medscape Medical News, Nov 02, 2022
Earlier Anticoagulation Better After Ischemic Stroke in AF?The observational ATTUNE study suggests that starting anticoagulation within 4 days of stroke leads to fewer new infarcts
detected by imaging without an increase in hemorrhage compared with starting later.
